{"id":127508,"date":"2024-03-08T12:28:41","date_gmt":"2024-03-08T17:28:41","guid":{"rendered":"http:\/\/kendallharmon.net\/?p=127508"},"modified":"2024-03-08T20:45:02","modified_gmt":"2024-03-09T01:45:02","slug":"sa-blocking-a-single-protein-could-prevent-nerve-damage-responsible-for-alzheimers","status":"publish","type":"post","link":"https:\/\/kendallharmon.net\/?p=127508","title":{"rendered":"(SA) Blocking a Single Protein Could Prevent Nerve Damage Responsible For Alzheimer&#8217;s"},"content":{"rendered":"<p>Scientists have identified a key protein in the development of Alzheimer&#8217;s disease which could prove critical in slowing or even halting the condition&#8217;s progress.<\/p>\n<p>In tests on mice, a research team led by University of Colorado pharmacologist Tyler Martinez found that blocking a protein called murine double-minute 2 (Mdm2) stopped the destruction of the protrusions or &#8216;dendritic spines&#8217; and junctions (synapses) that aid communication between brain cells.<\/p>\n<p>This degeneration is triggered by the build-up of a substance called amyloid-beta, which has long been linked to clogging up the brain in people with Alzheimer&#8217;s. When Mdm2 was deactivated, amyloid-beta no longer had the same effect.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/blocking-a-single-protein-could-prevent-nerve-damage-responsible-for-alzheimers\">Read it all<\/a>.<\/p>\n<blockquote class=\"twitter-tweet\">\n<p lang=\"en\" dir=\"ltr\">Blocking a Single Protein Could Prevent Nerve Damage Responsible For Alzheimer&#39;s <a href=\"https:\/\/t.co\/k4zF5jT2Ly\">https:\/\/t.co\/k4zF5jT2Ly<\/a><\/p>\n<p>&mdash; ScienceAlert (@ScienceAlert) <a href=\"https:\/\/twitter.com\/ScienceAlert\/status\/1765880459043492269?ref_src=twsrc%5Etfw\">March 7, 2024<\/a><\/p><\/blockquote>\n<p> <script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists have identified a key protein in the development of Alzheimer&#8217;s disease which could prove critical in slowing or even halting the condition&#8217;s progress. In tests on mice, a research team led by University of Colorado pharmacologist Tyler Martinez found<span class=\"ellipsis\">&hellip;<\/span><\/p>\n<div class=\"read-more\"><a href=\"https:\/\/kendallharmon.net\/?p=127508\">Read more &#8250;<\/a><\/div>\n<p><!-- end of .read-more --><\/p>\n","protected":false},"author":794,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[104,95],"tags":[],"class_list":["post-127508","post","type-post","status-publish","format-standard","hentry","category-health-medicine","category-science-technology"],"_links":{"self":[{"href":"https:\/\/kendallharmon.net\/index.php?rest_route=\/wp\/v2\/posts\/127508","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kendallharmon.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kendallharmon.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kendallharmon.net\/index.php?rest_route=\/wp\/v2\/users\/794"}],"replies":[{"embeddable":true,"href":"https:\/\/kendallharmon.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=127508"}],"version-history":[{"count":5,"href":"https:\/\/kendallharmon.net\/index.php?rest_route=\/wp\/v2\/posts\/127508\/revisions"}],"predecessor-version":[{"id":127513,"href":"https:\/\/kendallharmon.net\/index.php?rest_route=\/wp\/v2\/posts\/127508\/revisions\/127513"}],"wp:attachment":[{"href":"https:\/\/kendallharmon.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=127508"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kendallharmon.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=127508"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kendallharmon.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=127508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}