(Nature) World’s biggest set of human genome sequences opens to scientists

The world’s largest collection of full human genomes has just gone live.

The UK Biobank — a repository of health, genomic and other biological data — today released complete genome sequences from every one of the 500,000 British volunteers in the database. Researchers around the world can apply for access to the data, which lack identifiable details, and use them to probe the genetic basis for health and disease.

“Scientists are looking at this like Google Maps,” Rory Collins, the UK Biobank’s chief executive, said at a press briefing. “When they want to know what are the pathways from lifestyle, environment, genetics to disease, they don’t go Google, they go to UK Biobank.”

Today’s bonanza releases the complete 3-billion-letter genome sequence for every UK Biobank participant, and follows the 2021 release of whole genomes from 200,000 Biobank participants. The £200-million (US$250-million) effort was funded by the biomedical-research funder Wellcome, the UK government and several pharmaceutical companies — which, in return, got access to the data 9 months before their wider release.

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Posted in Health & Medicine, Science & Technology