(Yesterday’s NYT Front Page) Gasping For Breaths The Size Of A Tablespoon. 32 Days on a Ventilator: One Covid19 Patient’s Fight to Breathe Again

Mr. Bello’s cataclysmic spiral from avid skier, cyclist and runner to grievously ill patient — and the heartbreaking and triumphant twists in doctors’ relentless efforts to save him — underscores the agonizing challenges confronting even highly trained physicians and well-equipped hospitals battling a ferociously capricious virus.

Hospitals have never before had, simultaneously, so many patients so sick that their lungs have basically stopped functioning. And while doctors are experienced at treating similar respiratory failure, the path of patients with Covid-19 can be maddeningly unpredictable.

“It’s like they fall off a cliff,” said Dr. Peggy Lai, a critical care doctor at Mass General. “You see young patients getting sicker and sicker by the day despite everything that you know is good standard of care.”

Without proven therapies to extinguish the infection, doctors ride roller-coasters of trial and error. They weigh risks of uncertain treatments and painstakingly adjust machines in hopes of shoring up patients’ lungs enough that their bodies clear the inflammation and heal.

“The tricky part with this disease,” Dr. Lai said, “is that we have nothing to follow, to know what predicts how sick someone will be and what predicts them getting better.”

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