At 7.30 a.m. on Wednesday, Kristian Andersen, an infectious disease researcher at Scripps Research in San Diego, received a message on Slack: “This variant is completely insane.” Andrew Rambaut of the University of Edinburgh was reacting to a new SARS-CoV-2 genome sequence found in three samples collected in Botswana on 11 November and one picked up a week later in a traveler from South Africa to Hong Kong.

Andersen looked at the data and then replied: “Holy shit—that is quite something. The length of that branch…” A few minutes later he added: “Just had a look at the list of mutations—so nuts.”

They were talking about what is now called Omicron, a new variant of concern, and the long branch Andersen noticed refers to its distance to every other known virus on SARS-CoV-2’s evolutionary tree. The variant seemed to have picked up dozens of mutations, many of them known to be important in evading immunity or increasing transmissibility, with no intermediate sequences in the database of millions of viral genomes. On Tuesday, after spotting the odd sequences in a global database, Tom Peacock, a virologist at Imperial College London, had already posted his own verdict on GitHub: “This could be of real concern.”

Now, once again, the world is watching as researchers work nights and weekends to learn what a new variant has in store for humanity. Is Omicron more infectious? More deadly? Is it better at re-infecting recovered people? How well does it evade vaccine-induced immunity? And where did it come from? Finding out will take time, warns Jeremy Farrar, the head of the Wellcome Trust: “I’m afraid patience is crucial.”

Read it all.

Comprehensive article on Omicron's emergence. "Based on a comparison of different Omicron genomes, Andersen estimates that the virus emerged sometime around late September or early October, which suggests it might be spreading more slowly than it appears." https://t.co/Bb8kieNJyl

— Scott Gottlieb, MD (@ScottGottliebMD) November 28, 2021

For now, there’s no evidence that Omicron causes more severe disease than previous variants. And it’s also not clear yet how quickly Omicron can spread from person to person.

Some earlier variants, such as Beta and Mu, had evolved a strong ability to evade immune defenses. But they never became a serious threat to the world because they proved to be poor at transmitting.

Some mutations in Omicron suggest that it may indeed transmit well. Three mutations alter a region of the spike protein called the furin cleavage site, which is already known to help the spike protein attach more effectively to cells.

But Dr. Hanage said he was not yet convinced by the South African data that Omicron was running rampant across the country. “I think it’s too early to be definitive,” he said.

Read it all.

New 'Omicron' Variant Stokes Concern but Vaccines May Still Work – The New York Times https://t.co/g6iYz3Rqto

— Scott Gottlieb, MD (@ScottGottliebMD) November 27, 2021

A new coronavirus variant has been detected in South Africa that scientists say is a concern because of its high number of mutations and rapid spread among young people in Gauteng, the country’s most populous province, Health Minister Joe Phaahla announced Thursday.

The coronavirus evolves as it spreads and many new variants, including those with worrying mutations, often just die out. Scientists monitor for possible changes that could be more transmissible or deadly, but sorting out whether new variants will have a public health impact can take time.

South Africa has seen a dramatic rise in new infections, Phaahla said at an online press briefing.

“Over the last four or five days, there has been more of an exponential rise,” he said, adding that the new variant appears to be driving the spike in cases. Scientists in South Africa are working to determine what percentage of the new cases have been caused by the new variant.

Read it all.

South African scientists detect new virus variant amid spike https://t.co/3RIQaR1fDd

— Pittsburgh Post-Gazette (@PittsburghPG) November 26, 2021

Farmers and those living in rural areas have been urged to seek help and open up if they are suffering feelings of isolation, emptiness or despair, accepting that mental illness is nothing to be ashamed of and is highly treatable.

Answering questions at the NFU’s annual Henry Plumb Lecture, the Archbishop of Canterbury, Justin Welby, spoke candidly about his own experience of depression.

“I take anti-depressants. I see someone quite regularly,” he said. “For quite a long time my behaviour became so complicated that even my colleagues noticed it as being unusual.

“I made a joke of it, but depression is not a joke and is the most frequent form of mental illness, and is treatable for most people most of the time.”

Read it all.

Archbishop urges openness to counter farmers’ mental health challenges https://t.co/cXOpAwIFRY

— ukagri (@ukagri) November 24, 2021

Two weeks’ notice: Winston-Salem/Forsyth County Schools in North Carolina voted on Oct. 28 to close schools on Nov. 12 for a “day of kindness, community and connection.”

Five days’ notice: On the evening of Wednesday, Nov. 17, Ann Arbor Public Schools in Michigan announced that schools would be closed the following Monday and Tuesday, extending Thanksgiving break for a full week. The district cited rising COVID-19 cases and staff shortages.

Three and even two days’ notice: On Tuesday and Wednesday, Nov. 9 and 10, three different districts in Washington state — in Seattle, Bellevue and Kent — announced schools would be closed that same Friday, the day after Veterans Day, due to staff shortages.

Schools and districts around the country have been canceling classes on short notice. The cancellations aren’t directly for COVID-19 quarantines; instead schools are citing staff shortages, staff fatigue, mental health and sometimes even student fights.

Read it all.

“Do you care at all about my child progressing with reading, writing, math, social skills, etc? Because I do. It's not just about finding childcare.” https://t.co/RTPcPJqblg

— Josh Kraushaar (@HotlineJosh) November 23, 2021

As the first human trial begins, David Cox meets the scientists who say prevention, not cure, may be the answer

At Brigham and Women’s hospital in Boston, Massachusetts, Tanuja Chitnis is preparing to begin a clinical trial later this month, which represents a landmark moment in the fight against Alzheimer’s disease.

Chitnis, a professor of neurology at Harvard Medical School, is leading the first ever investigation in human patients to test whether a vaccine can prevent the progression of Alzheimer’s, the most common form of dementia. It works by clearing toxic forms of a protein called beta-amyloid which accumulates in the brain over many years. These eventually form plaques which disrupt normal brain function and lead to memory loss and confusion.

This is not a vaccine in its most conventional sense. While influenza and Covid-19 vaccines aim to prevent individuals from getting infected in the first place, the Alzheimer’s vaccine looks to mobilise the brain’s immune cells, called microglia, against these forms of amyloid. It is hoped that by doing so in patients in the very early stages of the disease, before too much damage has been done, it can be stopped in its tracks.

“The term vaccine is broad, and generally means utilising the immune system to combat disease,” explains Chitnis. “Here, we are activating a population of immune cells to clear beta-amyloid plaques.”

Read it all.

🧠 Alzheimer's Vaccine:

"The success of the trial – which will see 16 participants with early Alzheimer’s, aged between 60 and 85, receive two doses of the vaccine – will determine whether this approach offers a new frontier in treating the disease."https://t.co/UlrTuieuwn

— HumanProgress.org (@HumanProgress) November 23, 2021

South Carolina added more than 2,300 new COVID-19 cases over the past three days, the state Department of Health and Environmental Control reported Monday For three straight weeks, the state has seen fewer than 1,000 new daily cases. A similar streak of lower numbers hasn’t occurred since July, when daily case totals were at the lowest since the pandemic began. The Palmetto State’s downward trend of cases over the past month shows the spread of the virus has slowed significantly compared to months earlier.

Read it all.

More than 550 people have died in South Carolina from COVID-related issues over the past month. https://t.co/6vB9VbnW5g

— The State Newspaper (@thestate) November 22, 2021

Austria will again enter a nationwide lockdown and Germany is no longer ruling out a similar move as Europe grapples with a brutal wave of the coronavirus pandemic.

Austria will become the first western European country to impose widespread restrictions after curbs on unvaccinated people failed to stem a surge in new infections. It will also become the first European country to mandate Covid-19 shots as it seeks to exit the crisis.

Read it all.

Austria will enter its fourth nationwide lockdown on Monday as a record spike in Covid cases threatens to overwhelm the country’s health care system https://t.co/nuU5Eb85EP via @bpolitics @virtualnomad @naomikresge

— Robert Jameson (@rhjameson) November 19, 2021

To grow and spread, cancer cells must evade the immune system. Investigators from Brigham and Women’s Hospital and MIT used the power of nanotechnology to discover a new way that cancer can disarm its would-be cellular attackers by extending out nanoscale tentacles that can reach into an immune cell and pull out its powerpack. Slurping out the immune cell’s mitochondria powers up the cancer cell and depletes the immune cell. The new findings, published in Nature Nanotechnology, could lead to new targets for developing the next generation of immunotherapy against cancer.

“Cancer kills when the immune system is suppressed and cancer cells are able to metastasize, and it appears that nanotubes can help them do both,” said corresponding author Shiladitya Sengupta, PhD, co-director of the Brigham’s Center for Engineered Therapeutics. “This is a completely new mechanism by which cancer cells evade the immune system and it gives us a new target to go after.”

To investigate how cancer cells and immune cells interact at the nanoscale level, Sengupta and colleagues set up experiments in which they co-cultured breast cancer cells and immune cells, such as T cells.

Read it all.

Cancer cells use ‘tiny tentacles’ to suppress the immune system https://t.co/ooEpm6FhIh#science

— Bioengineer.org (@bioengineerorg) November 18, 2021

Germany is in the grip of a “dramatic” fourth Covid wave, Chancellor Angela Merkel has said on the eve of a crisis meeting with regional leaders.

Daily infections hit a new German record of 52,826 on Wednesday as European governments responded to a surge on much of the continent.

Belgium announced a series of measures in an attempt to avoid a lockdown.

“All the alarm signals are red,” said Prime Minister Alexander De Croo, as he told people to limit personal contact.

“Europe’s map is quickly going red, and we are the same.”

Children in Belgium will have to wear masks from the age of 10, rather than the current age of 12. Working from home will become compulsory from Saturday for four days a week. Passes known as Covid Safe Tickets will be required in theatres, cinemas and museums.

For months, the putt-putt course sat unused. The beanbag chairs lay empty. The kitchen whiteboard, above where the keg used to live, displayed in fading marker “Beers on Tap” from a happy hour in March 2020.

But on a recent weekday, over in the common area was a sign of life — fresh bagels.

As employees at the financial technology start-up CommonBond got Covid vaccines, and grew stir-crazy in their apartments, they started trickling back into the office.

“We call it Work From Work Wednesday,” said Keryn Koch, who runs human resources at the company, which has 15,000 square feet of sunlit SoHo real estate.

At one point, autumn had been billed across corporate America as the Great Office Reopening. The Delta variant intervened, and mandatory return-to-office plans turned optional. Still, many people chose to report back to their desks: The share of employed people who worked remotely at some point during the month because of Covid, which had peaked in May 2020 at 35 percent, dropped in October to 11 percent, the lowest point since the pandemic began, according to the Bureau of Labor Statistics.

Read it all.

Many companies are grappling with how to balance the needs of their remote and in-person employees as people trickle back to offices. Many workers are in the mushy middle ground, with flexibility, and all the benefits it confers, at stake.https://t.co/gkvnL8ZCuj

— The New York Times (@nytimes) November 16, 2021

Nearly Two in Five Pastors Have Considered Quitting Full-Time Ministry

With pastors’ well-being on the line, and many on the brink of burnout, 38 percent indicate they have considered quitting full-time ministry within the past year. This percentage is up 9 full points (from 29%) since Barna asked church leaders this same question at the beginning of 2021.

A deeper analysis of these data show that some groups are faring worse than others. One of the more alarming findings is that 46 percent of pastors under the age of 45 say they are considering quitting full-time ministry, compared to 34 percent of pastors 45 and older. Keeping the right younger leaders encouraged and in their ministry roles will be crucial to the next decade of congregational vitality in the U.S.

Another notable gap emerges based on denomination, with pastors from mainline denominations far more likely to consider quitting than those from non-mainline denominations (51% vs. 34%). Other significant differences arise among gender, with female pastors being far more likely than male pastors to have considered giving up full-time ministry, and ministry tenure. Specifically, roughly one-third of pastors who are considering resignation have been in ministry for about 20 years but have been at their current church for seven years.

Read it all.

[NEW STUDY]

38% of U.S. Pastors Have Thought About Quitting Full-Time Ministry in the Past Year

Up from 29% in January.

What do you think about this?https://t.co/qFGAPsqDCn

— David Kinnaman (@davidkinnaman) November 16, 2021

As temperatures drop and coronavirus infections spike across Europe, some countries are introducing increasingly targeted restrictions against the unvaccinated who are driving another wave of contagion and putting economic recoveries, public health and an eventual return to prepandemic freedoms at risk.

On Monday, Austria set a new bar for such measures in the West. Facing a 134 percent increase in cases in the last two weeks, the Austrian government cracked down on its unvaccinated population over the age of 12, restricting their movement to traveling for work, school, buying groceries and medical care.

“Our task as the federal government is to protect the people of Austria,” Chancellor Alexander Schallenberg told a news conference on Sunday. “We are fulfilling this responsibility.”

Read it all.

European countries are introducing increasingly targeted rules and measures to make life harder for the unvaccinated, with the goal of motivating them to get a shot. https://t.co/nFftS9iFP7

— The New York Times (@nytimes) November 15, 2021

Where is everybody?

Why are so many from our church not attending like they did before COVID-19?

Why are we having to contact them multiple times, offer food, plan special events just to get them to come in person?

We shouldn’t have to do this!

Thoughts similar to these have likely been going through your head in recent months. Few churches are back to pre-COVID attendance. In fact, the average Protestant church has in-person attendance of 73% of their pre-COVID attendance. While that’s an improvement over early in 2021 when an average of 60% of pre-COVID attendees were coming to church in person, it can still be frustrating for pastors and church leaders.

How should we process this news that so many churchgoers are missing on a typical week? What should we make of this reality?

Read it all.

The average Protestant church's in-person attendance is 73% of their pre-pandemic attendance. https://t.co/fSGtKAbDPX

— Lifeway Research (@LifewayResearch) November 13, 2021

‘Home Base, a Red Sox Foundation and Massachusetts General Hospital program, is helping veterans access therapy and critical mental health care. NBC News’ Cynthia McFadden speaks with a psychologist who helps run the program, and two veterans who took part in a two-week intensive program funded by the Wounded Warrior project.’

Watch it all.

Charleston County School District decided its mask mandate will end on Nov. 10, allowing students, staff and visitors to go to schools without face coverings.

The district’s school board voted overwhelmingly in favor of ending its mask policy during a Nov. 8 meeting, citing a low spread of the COVID-19 virus and the recent availability of vaccines for children ages 5 to 11.

The district reported only 38 cases among about 50,000 students and staff members over the week of Nov. 1 — the eighth consecutive week cases fell. During its peak the week of Aug. 30, there were 473 cases reported among students and staff members.

The district is following guidance from doctors at the Medical University of South Carolina, which said that it’s reasonable to unmask when spread of the virus is low in the community. The COVID-19 activity in Charleston County is currently rated “low” by the S.C. Department of Health and Environmental Control.

Read it all.

From P&C: Charleston County School Board votes to end mask requirement https://t.co/JlAejY9CR9 #chsnews

— Sam Tyson (@SamInteractive) November 9, 2021

Canada’s Medical Assistance in Dying (MAiD) act began to operate in 2016. It is a laboratory for how legalised euthanasia will operate in a largely English-speaking country. And, according to an article in the journal Palliative Care written by five Canadian specialists, it has had a very negative effect upon palliative care.

The authors interviewed 13 doctors and 10 nurses about their impressions. Some of the feedback is unexpected.

First, all of them spoke about an inherent conflict between the provision of palliative care (PC) and eligibility for MAiD. To ensure that their patients remained eligible, they had to withhold medications which would have otherwise removed or alleviated their pain. “Maintaining lucidity and eligibility for assisted death, by avoiding sedative medications, took priority over achieving good symptom control for some patients,” they write. Both the patients and the PC providers found this distressing.

Read it all.

"13 #doctors and 10 #nurses… spoke about an inherent #conflict between the provision of #palliativecare (PC) and eligibility for #MAiD. To ensure that their #patients remained #eligible, they had to withhold [#pain] #medications" https://t.co/xd1X3UHJXU#nursing #medical #VAD

— BioEdge (@bioedge) November 8, 2021

Mr. Biden came into office vowing to “build back better.” But voters said little was getting built as Democrats fight over multitrillion-dollar measures to strengthen the country’s social safety net and improve physical infrastructure. Normal life was not back, and might never be. And voters said so many things just felt worse.

It is not just the federal government they blame. Trash is piling up on city streets because of a dearth of garbage haulers. School bus services are being canceled and delayed for want of drivers. Americans who have been hurt economically by the pandemic are still struggling to get rental assistance and unemployment benefits, sometimes months after applying.

“Our political system — it’s almost completely a failure,” said Carla Haney, a 65-year-old swimming instructor who has yet to receive about 14 weeks of unemployment benefits from the State of Florida that she applied for in May 2020. “I don’t see it getting better at all.”

With the global supply chain gummed up, voters around the Phoenix metro area said they were paying the price in lost money and wasted time. A restaurant chef in Phoenix is once again struggling to buy paper plates and napkins. A plumbing supplier in Tempe is losing commissions because he cannot fill orders.

And at gas stations across the country, drivers cringe at paying an average of $3.40 a gallon — prices that have risen by more than $1 a gallon from a year ago.

Read it all.

“It’s just not a civilized country,” said Ted Laarkamp, 76, a retired businessman from Media, Penn. “It’s just a bunch of people that think they can go it alone — like a bunch of lone rangers. Nobody trusts anybody; everything is a conspiracy.” https://t.co/cdj1et5xSz

— Kate Kelly (@katekelly) November 6, 2021

Google owner Alphabet has launched an artificial intelligence company to discover new drugs.

UK-registered Isomorphic Labs will use technology from its sister company DeepMind “to accelerate drug discovery, and ultimately, find cures for some of humanity’s most devastating diseases,” said Demis Hassabis, the head of DeepMind, in a blog post. He added that he would also become the chief executive of Isomorphic Labs.

Scientists around the world were awed in July when DeepMind unveiled how its AlphaFold2 technology could be used to predict the shape of every protein in the human body with almost perfect accuracy.

DeepMind’s model can solve one of the trickiest problems in biology by taking a sequence of amino acids and mapping the twists and turns of its shape. The algorithm could help replace or enhance painstaking laboratory work to identify the structures of proteins, which dictate how they behave.

Read it all.

Alphabet launches AI company to discover new drugs https://t.co/DCdq8DOHCO "DeepMind said it would use the technology to try to find treatments for Chagas disease and Leishmaniasis, two of the most deadly diseases in the world."

— Kristof Decoster (@KristofDecoste1) November 4, 2021

Tucked away in a northern suburb of this sprawling East African city is a burial site that is evidence of one of the world’s great coronavirus coverups.

At the Kondo graveyard in Dar es Salaam, Tanzania, unmasked volunteers have been digging holes and felling trees to expand a compound that has tripled in size since last year. During the pandemic’s first wave, hazmat-suited government officials came at night to secretly bury the dead, graveyard workers and bereaved families said. Now, small groups of mourners gather for hasty ceremonies next to floral tributes.

Kondo’s gravediggers said those buried there since last year have one thing in common: All died as a result of the coronavirus, yet none were recorded as suffering from Covid-19. They said they know by speaking to the families and officials from the municipality.

“This is one of the government’s coronavirus cemeteries, but we’re not allowed to call it that,” said Said Ali Salum, a caretaker who has worked there so long that locals call him “Mzee Wa-Makaburi,” or Mr. Graveyard. “We used to bury one a week [before the pandemic], but over the past year we have reached 17 a day.”

Tanzania, a country famous for Serengeti safaris and a turquoise coastline, has engaged in a grim experiment with implications beyond its borders: denying the existence of Covid-19. How that is playing out offers clues on the hidden toll of the pandemic across the developing world.

Read it all.

Take an early look at the front page of The Wall Street Journal https://t.co/5xQPDPcm8q pic.twitter.com/ltEVZ0YLvH

— The Wall Street Journal (@WSJ) November 5, 2021

Americans’ outlook for the coronavirus pandemic in the U.S. has improved, as the summer surge brought on by the delta variant has waned in most parts of the country. The percentage of Americans who now say the U.S. COVID-19 situation is improving has more than doubled between September and October, to 51%.

Over the same period, worry about contracting the virus has edged down four percentage points, to 36%, and concern about the availability of hospital supplies, treatment and services has tumbled 10 points, to 33%. Although the public is more optimistic about the current state of the pandemic, a majority thinks the disruption to life will continue throughout 2022 or longer than that.

These findings are from an Oct. 18-24 update of Gallup’s COVID-19 survey, which interviewed more than 4,000 members of its probability-based panel by web. Interviewing was conducted at a time when COVID-19 cases, hospitalizations and deaths were down sharply from the most recent peak.

Read it all.

36% of Americans are worried about getting COVID-19, down slightly from September and October but higher than it was from April through July. https://t.co/qDKYDMbopt

— GallupNews (@GallupNews) November 3, 2021

Two middle school students are being praised for their quick action when their bus driver experienced a medical emergency.

Conner Doss and Kane Daugherty are students at East Paulding Middle School outside Atlanta and were on a full bus when the incident happened, according to CNN affiliate WSB-TV.
“I come out, I come in the aisle and look down. Miss Julie’s face is bright red and shaking,” Doss told WSB.

The driver managed to pull over and that’s when they realized something was wrong.

“I hear her say, ‘Hey! Somebody help!’ So, I run up. She’s over here shaking really bad,” said Daugherty. “I picked up the [dispatch radio], I said, ‘Somebody help. Our bus driver feels really dizzy.’ Somebody called her phone.”

The dispatcher was able to call 911, help the boys set the emergency brake, flashing lights and emergency stop arm.

Read it all.

"Because of their quick and decisive actions, a potentially dangerous situation was avoided."https://t.co/7oudoIzlhK #Look4Lykke #FindTheGood

— Jade Walker (@jadewalker) October 28, 2021

When Dr. Robert Stuart first arrived at the Medical University of South Carolina from Johns Hopkins in 1985, the Hollings Cancer Center wasn’t even a far-flung dream.

That’s because there was no oncology department to speak of at MUSC back then. There weren’t even board-certified oncologists on the full-time faculty. Stuart was the first one the hospital ever hired.

MUSC, he acknowledged, was late to the game.

“Roper had probably four or five (oncologists),” Stuart said. “That aspect of cancer medicine here (at MUSC) was almost non-existent.”

Read it all.

Born in Baton Rouge and raised in rural Louisiana, Dr. Robert Stuart's long oncology career in many ways demonstrates how cancer care has been transformed over the past several decades.https://t.co/1vo3zmJCY3

— The Post and Courier (@postandcourier) October 29, 2021

Today marks the start of a formal period of Listening and Engagement which will run until Friday 10 December. The Commission wants to hear from a wide range of individuals and organisations and ensure that its work is shaped by the views and voices of people and organisations who have experience of care and care giving.

They are calling for contributions from:

• Those who draw on formal services
• Unpaid carers, and the relatives and friends of those who draw on care and support
• Those who work in the care sector and the voluntary and community sector
• Churches of all denominations and other faith communities
• Those who commission, provide and regulate formal services
• Community groups and people who provide informal support

The consultation launched today aims to gather views about the challenges experienced by those currently drawing on care and support and those who work in the sector.

They are also interested in identifying examples of good practice.

The Commission is particularly interested in the role that communities play in supporting people with disability and in later life to live well, in particular the role of church and other faith communities.

Read it all.

The Archbishops’ Commission on Reimagining Care launches its survey today – help shape the Church’s long-term vision for care and support by telling us your thoughts about ageing, disability and our humanity in the light of who God is. https://t.co/EvJf3H5RCL pic.twitter.com/OJwMtzvLu6

— Stephen Cottrell (@CottrellStephen) October 27, 2021

“Nobody will ever forget this past January, but now Covid is endemic and we need to learn to live with the virus,” said Dr. Mota. “Almost the whole population is vaccinated here and the virus still circulates, showing it won’t go away.”

As in other countries with a large proportion of the population vaccinated, a stubborn persistence of infections in Portugal hasn’t led to a significant increase in the rate of hospitalizations or deaths.

“Things are getting better, but it’s slow,” said Miguel Campos, who drives tourists around Lisbon in a tuk-tuk. “We are taking baby steps. We have a mix of optimism and hope that this return to normal will continue.”

Before the pandemic there were 800 rickshaw taxi drivers in Lisbon, but now only about 200 work during the week and 500 on weekends, said Valentim Gaspar, another rickshaw taxi driver. For now, the balance between drivers and tourists makes it possible to earn a decent living, he said.

The Portuguese almost universally attribute their vaccination success to Henrique Gouveia e Melo, an ex-submarine commander brought on to run the inoculation drive after a shaky start. He projected confidence and tapped into the population’s generally favorable attitudes to vaccinations, according to public-health experts. The vaccine rollout began in January just as the worst of the pandemic peaked in Portugal, providing a clear incentive for anybody who might have been unsure about getting vaccinated.

Read it all.

With one of the world’s highest Covid-19 vaccination rates, Portugal is learning to live with the virus and being watched by other countries as a possible way forward https://t.co/Qbnn4PYiTa

— The Wall Street Journal (@WSJ) October 25, 2021

Sadly, I believe this Bill to be unsafe. As a curate and parish priest I spent time with the dying, the sick and the bereaved. I still do. All of us have personal experience. I have as well. We know that the sad truth is that not all people are perfect, not all families are happy, not everyone is kind and compassionate. No amount of safeguards can perfect the human heart, no amount of regulation can make a relative kinder or a doctor infallible. No amount of reassurance can make a vulnerable or disabled person feel equally safe, equally valued, if the law is changed in this way.

All of us here are united in wanting compassion and dignity for those coming to the end of their lives.

But it does not serve compassion if by granting the wishes of one closest to me, I expose others to danger.

And it does not serve dignity if in granting the wishes of one closest to me I devalue the status and safety of others.

Read it all.

No amount of reassurance can make a vulnerable or disabled person feel equally safe, or equally valued, by the changes that the Assisted Dying Bill seeks to make.https://t.co/Lnl7elrR7U

— Archbishop of Canterbury (@JustinWelby) October 22, 2021

We largely have Christianity to thank for our faltering modern belief that human life is sacred. The ancients took a much more casual approach. Unwanted babies were abandoned to die or be rescued by strangers: like Romulus and Remus, Rome’s mythical founders, who were raised by a wolf.

Much as new lives were not automatically worth preserving, taking your own life in the ancient world wasn’t automatically bad either. Socrates’ decision to drink hemlock rather than face exile, was deemed honourable by many ancient philosophers.

Christian doctrine, though, taught that human life is sacred, because it holds a spark of the divine. Thus only God should be permitted to give or take life. The 325AD Council of Nicaea decreed that every Christian village should have a hostelry for the sick, a principle which extended to abandoned children. For the same reason, a long-standing Christian tradition forbids suicide. But as the Christian era has faded, so old debates about the beginning and end of life have re-surfaced – most recently, in the accelerating campaign to legalise assisted dying.

Read it all.

An excellent and very moving piece from @moveincircles in @unherd, with a historical view to what happens when societies sacrifice the worth of each human life on the altar of the supposed prize of "choice". @holland_tom might find this interesting! https://t.co/ctHMpgQrzN

— Lois McLatchie (@LoisMcLatch) October 22, 2021

In the coming days this issue will return to Parliament as Baroness Meacher seeks to bring forward legislation which will allow assisted dying.

Or, in the words of some opponents of the Bill, it will enable state-approved euthanasia.

Previous attempts at changing legislation have argued that such a move would offer empowerment to the dying and increase choice for those with life limiting conditions on how to end their lives.

But the impact of enabling such choice has consequences which we have seen elsewhere in countries which have already gone down this road. In Belgium and the Netherlands, where assisted dying laws were passed under the banner of enabling choice for those with terminal conditions, assisted deaths are now legal on the basis of mental illness, learning disability and autism. Is it any wonder that of the 12 organisations representing disabled people in the UK none of them supports an Assisted Dying Bill?

Read it all.

My piece for @TheNorthernEcho ahead of Friday's debate in the House of Lords.
We should assist people to live – not to die https://t.co/wy7UDHAqpm

— Arun Arora (@RevArun) October 20, 2021

Surgeons in New York have successfully attached a kidney grown in a genetically altered pig to a human patient and found that the organ worked normally, a scientific breakthrough that one day may yield a vast new supply of organs for severely ill patients.

Researchers have long sought to grow organs in pigs that are suitable for transplantation into humans. Technologies like cloning and genetic engineering have brought that vision closer to reality in recent years, but testing these experimental organs in humans has presented daunting ethical questions.

So surgeons at N.Y.U. Langone Health took an astonishing step: With the family’s consent, they attached the pig’s kidney to a brain-dead patient who was kept alive on a ventilator, and then followed the body’s response while taking measures of the kidney’s function. It is the first operation of its kind.

The researchers tracked the results for just 54 hours, and many questions remained to be answered about the long-term consequences of such an operation. The procedure will not be available to patients any time soon, as there are significant medical and regulatory hurdles to overcome.

Read it all.

A kidney from a genetically engineered pig appeared functional after attachment to a human, scientists announced on Tuesday. If the research pans out, a vast new stream of organs for transplantation eventually may be available to desperate patients. https://t.co/iJN4c36WdC

— NYT Science (@NYTScience) October 20, 2021